Panama: CDN Gov warning (regional)

Regional Advisory for the region beyond Yaviza
Foreign Affairs and International Trade Canada advises against all travel beyond the town of Yaviza in Darién Province. The area begins at the end of the Pan-American Highway (past Yaviza, about 230 kilometres southeast of Panama City) and ends at the Colombian border. This area includes parts of Darién National Park and privately owned nature reserves and tourist resorts. Due to the presence of Colombian guerrilla groups and drug traffickers, the level of violent crime in this zone is extremely high, with numerous reports of kidnappings, armed robberies, deaths and disappearances.

Read more:
http://travel.gc.ca/destinations/panama